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Three-dimensional reconstruction of rigor insect flight muscle from tilted thin sections

Abstract

Rigor cross-bridges show two conformations paired within each 38.7-nm axial repeat. The two forms may express two stages of the cross-bridge cycle during contraction. Differing numbers of myosin heads per cross-bridge and associated helical changes in the thin filament distinguish the two forms and suggest that both myosin heads usually bind to a single thin filament.

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Taylor, K., Reedy, M., Córdova, L. et al. Three-dimensional reconstruction of rigor insect flight muscle from tilted thin sections. Nature 310, 285–291 (1984). https://doi.org/10.1038/310285a0

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