Figure 5
From: A pilot study to explore circulating tumour cells in pancreatic cancer as a novel biomarker
CTCs and CTMs captured on ISET filters. (A–C) Three different patient samples, filtered through ISET membranes (pores are dark circles) and stained with CD45 antibody so that leukocytes can be excluded; these are shown in brown. Circulating tumour cells were counterstained with haematoxylin. (C) A large CTM. The membrane pores are all 8 μm in diameter, which gives scale to these images. (D) A CTM from patient 39 (pancreatic head primary and liver, lung and abodminal wall metastases) demonstrates similar morphology to (E). (E) A haematoxylin and eosin (H&E)-stained tumour block from the same patient photographed at the same magnification.
