Figure 3
Effect of epinephrine on Pt behaviour during PIPC. (A) The effect of epinephrine on individual rate of transfer of Uf Pt from peritoneum to bloodstream. (B) Assessment of the effect of epinephrine on the individual Pt penetration. 3x0 (μm) is the distance in peritoneal tissue at which the concentration difference between tissue and blood perfusing this tissue decreased to 5% of its maximal value. (C) Time during which the IP Pt concentration is over 10 mg l–1. The data were obtained for patients treated with cisplatin with (white box) or without (grey box) epinephrine. ‡ means P<10−4 (t-test) as compared with values observed without epinephrine.
