Figure 2
From: Functional imaging: what evidence is there for its utility in clinical trials of targeted therapies?

Dynamic contrast enhanced-MRI parametric maps before (left column) and 28 days after (right column) VEGF inhibitor therapy in a patient with metastatic colorectal carcinoma illustrating a down-stream effect with significant reduction in tumour vascularity (Courtesy to Dr C Messiou & M Orton, Royal Marsden Hospital).