Figure 1 | British Journal of Cancer

Figure 1

From: Effect of aerobic training on the host systemic milieu in patients with solid tumours: an exploratory correlative study

Figure 1

Aerobic training prescription and efficacy. (A) Nonlinear aerobic training prescription. Supervised aerobic training consisted of three supervised aerobic cycle ergometry sessions per week, 20–45 min per session, at 55% to 100% of peak oxygen consumption (VO2peak), on nonconsecutive days for 12 weeks. Aerobic training intensity was based on the workload (W) corresponding to a specific percent of VO2peak (e.g., 55%, 65%) elicited during the prerandomisation cardiopulmonary exercise test and was designed to improve VO2peak. Specifically, intensity is depicted by the coloured bars as a percentage of VO2peak: (1) black 55–60%, (2) blue 65–70%, (3) orange 70–80%, and (4) red 100%. Grey-coloured bars represent rest (off) days. In weeks 1–4, black and blue exercise sessions were ∼20–30 min in duration; in weeks 5 to 8, black and blue sessions were ∼30–45 min in duration, whereas orange sessions were for ∼20 to 25 min. In weeks 9 to 12, black and blue sessions were ∼30–45 min in duration, orange sessions were ≥25 min, whereas red sessions consisted of interval sessions for 30 s at 100% VO2peak followed by 60 s of active recovery at ∼50% VO2peak for 10–20 intervals. (B) Effect on VO2peak. Effect of aerobic training compared with usual care on delta change in mean absolute difference in VO2peak. Values are mean±s.d. (n=21–23 per group). *P<0.05. A full colour version of this figure is available at the British Journal of Cancer journal online.

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