Figure 1

Overview of the metabolomic data. (A) A total of 641 metabolites were identified in the study. (B) Principal component analysis revealed five outlier samples (circle) and grouping of leiomyomas of the FH subtype together, while the rest of the samples were intermixed. Venn diagrams illustrating the number of significantly (C) increased and (D) decreased metabolites (q-value <0.1) among leiomyomas of the FH, MED12, HMGA2, and triple wild-type subtypes.