Table 3 Empirical P-values for association of INHBC polymorphisms and selected strength measurements

From: Comprehensive fine mapping of chr12q12-14 and follow-up replication identify activin receptor 1B (ACVR1B) as a muscle strength gene

 

Marker

 

rs7964492 a

rs12826906

rs560048

rs533975 a

rs2943693 a

rs2229357

rs3741414 a

Strength increasing allele

  

T

A

A

  

Knee flexion

 Isometric at 150°, Nm

0.52

0.68

0.17

0.27

0.43

0.35

0.32

 Isometric at 120°, Nm

0.60

0.63

0.40

0.49

0.57

0.40

0.39

 Torque at 60°/s, Nm

0.70

0.14

0.068

0.047

0.040

0.72

0.61

 Torque at 120°/s, Nm

0.70

0.86

0.056

0.048

0.11

0.73

0.76

Knee extension

 Isometric at 150°, Nm

0.095

0.68

0.092

0.066

0.57

0.25

0.22

 Isometric at 120°, Nm

0.23

0.60

0.096

0.16

0.58

0.12

0.14

 Torque at 60°/s, Nm

0.66

0.47

0.19

0.15

0.0039

0.43

0.49

 Torque at 120°/s, Nm

0.50

0.64

0.41

0.23

0.021

0.39

0.42

  1. Significant P-values are marked in boldj;
  2. aFour selected tagging SNPs.
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