Table 3 In vivo inhibition of LPS induced TNF-α by KBH-A42.

From: Histone deacetylase inhibitor KBH-A42 inhibits cytokine production in RAW 264.7 macrophage cells and in vivo endotoxemia model

  1. aBALB/c mice (four per group) were treated. KBH-A42 was pretreated twice (i.p. or p.o.) at 24 h and 2 h before LPS (1.5 mg/kg, i.p.) was injected. Serum TNF-α was measured after 60 min.
  2. *P < 0.05; **P < 0.01
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