Figure 5 | Experimental & Molecular Medicine

Figure 5

From: Transcriptional induction of DLC-1 gene through Sp1 sites by histone deacetylase inhibitors in gastric cancer cells

Figure 5

p300 is involved in the TSA-mediated DLC-1 promoter activation. p300 expression vector or pSuper vector carrying the shRNA against p300 (pSuper-p300) were cotransfected with the DLC-1 promoter luciferase construct (-577/+117-pGL3b) into SNU-668 cells and treated cells with DMSO or 330 nM TSA for 12 h before measuring luciferase activity. Data are representative of two independent experiments performed in triplicate.

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