Figure 1
From: The presence of high level soluble herpes virus entry mediator in sera of gastric cancer patients

GC patients have lower mHVEM levels in their leukocytes and higher sHVEM levels in their sera than healthy controls. (A) Histogram of mHVEM expression in monocytes and neutrophils. Monocytes and neutrophils of GC patients and healthy controls were purified as described in Methods. Cells were stained with FITC-conjugated anti-HVEM antibody (open histogram) or isotype control (filled histogram) and analyzed by FACS. Results shown are representative of three experiments. (B) Percentages of HVEM-expressing monocytes (left panel) and neutrophils (right panel) in GC patients and HC were determined as in A. Each dot represents the % of HVEM expressing cells in a sample. Horizontal bars depict means. (C) sHVEM levels in sera of GC patients and HC. Concentrations of sHVEM in sera were determined by ELISA as described in Methods. Horizontal bars depict means. Each datum shown is the mean of triplicate measurements. ***P < 0.001 compared with control groups.