Figure 5

Protective effect of adoptive transfer of sera and splenocytes from K. pneumoniae EV-immunized mice against lethal K. pneumoniae infection. Challenge with the bacteria was performed 24 h after the serum or splenocytes were transferred to the naive mice. Survival graph of serum or splenocyte transferred mice after challenged with 2.5 × 107 CFU of bacteria (a) and 5 × 107 CFU of bacteria (b) (n=10, each group; *P<0.05, **P<0.01 and ***P<0.001, compared with the sham group).