Table 2 Properties of primary skeletal myotubes with sildenafil treatments

From: The maintenance ability and Ca2+ availability of skeletal muscle are enhanced by sildenafil

 

Untreated

DMSO

Sildenafil

KCl response

1.00±0.06 (119)

1.00±0.07 (129)

1.14±0.07a (144)

Caffeine response

1.00±0.06 (119)

0.99±0.07 (129)

1.18±0.07a (144)

Releasable Ca2+ from the SR

1.00±0.05 (68)

0.97±0.05 (62)

1.03±0.05 (64)

Resting [Ca2+]cytosol, nM

87.20±5.23 (99)

90.37±7.51 (110)

112.86±8.03a (103)

  1. Abbreviations: DMSO, dimethyl sulfoxide; SR, sarcoplasmic reticulum
  2. aSignificant difference compared with the untreated control (P<0.05).
  3. The values, except for those of resting cytosolic Ca2+ levels, were normalized to the mean value of those from the untreated controls. The values are presented as the mean±s.e. for the number of myotubes shown in parentheses.
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