Figure 5
From: Therapeutic inhibition of SGK1 suppresses colorectal cancer
p27 is involved in the SGK1 signaling pathway for the regulation of HT29 cell proliferation. (a) p27 mRNA levels in HT29 cells treated with SGK1 overexpression plasmids or SGK1 inhibitor GSK650394; (b) P27 and SGK1 protein expression levels. (c) Relative percentage changes of the proportion of EdU-positive cells compared to control; scale bars, 200 μm; n=4. (d) HT29 cell cycle analysis; n=4. #, 0.01<P<0.05; **, 0.001<P<0.01; *** and ###, P<0.001.
