Figure 6

BLT2 D196G leads to enhanced ligand binding affinity. (a–c) Binding affinities of each ligand for BLT2 were measured as described in the Materials and Methods section. Binding parameters were determined with Prism software, and data are presented as means±s.d.; n=3 independent experiments. *P<0.01 and **P<0.005 according to Student’s t-test. The t-test was performed to determine whether the difference was significant between BLT2 and BLT2 D196G with a ligand concentration of 10 nM.