Table 2 Solubility and cytotoxicity of 1 and 2

From: A pair of sulfur-containing geldanamycin analogs, 19-S-methylgeldanamycin and 4,5-dihydro- 19-S-methylgeldanamycin, from Streptomyces hygroscopicus 17997

Compound

Solubility (μg ml−1)

IC50 (μmol l−1)

GDM

2.0

0.062

1

2019

19

2

2132

23