Figure 2 | Laboratory Investigation

Figure 2

From: Flow cytometry analysis of synaptosomes from post-mortem human brain reveals changes specific to Lewy body and Alzheimer’s disease

Figure 2

Flow cytometry analysis of synaptosome preparation of human striatum from control (n=5), LBD (n=5), AD (n=11) and μVBI±AD (n=3) groups labeled with an antibody against DAT. (a) Percentage of DAT-positive particles in striatal synaptosomes of all groups. (b) DAT-positive particles in striatal synaptosomes of individual patients with LBD compared with average number of DAT-positive particles in control and combined AD+μVBI±AD groups. (c) Percentage of DAT-positive particles in the DLC plotted against percentage of DAT-positive particles in the VMC. (d) Percentage of DAT-positive particles in the averaged DLC and VM caudate nucleus synaptosomes plotted against percentage of DAT-positive particles in PT synaptosomes. All data are presented as mean±s.e.m. *P<0.05. Significant pairwise comparisons of groups are indicated by brackets.

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