Figure 2: Characteristics of a gene-rich (a) and a gene-poor (b) region.
The overlapping tilepath, labelled by accession number, is shown in yellow. Genetic markers from the deCODE map have been positioned on the sequence. Occurrences of repeats are shown as vertical turquoise bars. G + C content and CpG dinucleotide content are shown in overlapping windows of 8 kb, with adjacent windows overlapping by 4 kb. CpG islands are predicted using a modification of the CpG program developed by G. Micklem (personal communication). The positions of transcription start sites were predicted by the Eponine49 program. Regions conserved in mouse and rat are shown by orange bars, and those conserved in Fugu, Tetraodon and zebrafish are shown by green bars. The Rfam track contains the predicted ncRNA genes. Annotated gene structures are shown, sub-divided into categories by colour. The direction of transcription is indicated by the arrow. The SNP tracks indicate the number of SNPs per kb. The random SNPs were generated by the whole-genome shotgun approach and were obtained from dbSNP by querying for SNPs produced by The SNP Consortium50. The locations of clusters of two or more related genes within 1 Mb of each other are indicated. The scale shows the approximate Mb position along the chromosome. The chromosome view is available in Supplementary Fig. S1.
