Figure 3: Comparison of mutational classes between primary tumours and relapse samples.
From: Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing
a, Fraction of the primary tumour and relapse-specific mutations in each of the transition and transversion categories. b, Transversion frequencies of the primary tumour and relapse-specific mutations from eight AML tumour and relapse pairs. 456 relapse-specific mutations and 3,590 primary tumour mutations from eight cases were used for assessing statistical significance using proportion tests.
