Figure 1: Receptor binding properties. | Nature

Figure 1: Receptor binding properties.

From: Biological features of novel avian influenza A (H7N9) virus

Figure 1

a–c, Dose-dependent binding of A/Shanghai/1/2013 (a), A/Shanghai/2/2013 (b) and A/Anhui/1/2013 (c) viruses to both α2,3 and α2,6 glycans at the concentration of 0, 0.156, 0.3125, 0.625, 1.25 and 2.5 μg ml−1 sialylglycopolymers. d, The binding pattern of H7N9, H5N1 (A/Anhui/01/2005) and pandemic H1N1 (A/California/07/2009) viruses were exhibited at 2.5 μg ml−1. H5N1 data were obtained previously, as H5N1 and H7N9 viruses cannot be simultaneously handled owing to biosafety reasons. Results denote mean ± s.e.m. from two separate assays performed in duplicate. 3′SLN, Neu5Acα2-3Galβ1-4GlcNAc; 3′SLN-LN, Neu5Acα2-3(Galβ1-4GlcNAcβ1-3)2; 6′SLN, Neu5Acα2-6Galβ1-4GlcNAc; 6′SLN-LN, Neu5Acα2-6(Galβ1-4GlcNAcβ1-3)2.

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