Extended Data Figure 6: Periplasmic loops bind to BamA POTRA 3, 5, BamD and BamE.
From: Structural basis of outer membrane protein insertion by the BAM complex
In the BamABCDE complex, the BamA barrel interacts with POTRA 3, 5, BamE and BamD through the periplasmic turns T-1, -2, -3, -5, -6 and -7. a, In the BamABCDE complex, the residues of T-1, -2 and -3 are involved in the interactions with POTRA 5, BamD and BamE. b, Residues in T-5, -6 and -7 interact with POTRA 3 in the BamABCDE complex. c, In the BamACDE complex no interactions are observed between the periplasmic turns and POTRA 3. The figure shows that the residues in T-1, -2 and -3 interact with residues in POTRA 5, BamD and BamE. These structural data may suggest that BamB, C, D and E either directly or indirectly control the conformation of the barrel through its periplasmic turns.
