Extended Data Figure 8: Phenotyping of Spns2 lungs.
From: Genome-wide in vivo screen identifies novel host regulators of metastatic colonization
a, b, Ex vivo re-stimulation (PMA/ionomycin) of pulmonary leukocytes from B16-F10-stimulated +/+ and tm1a/tm1a female mice (two-tailed unpaired t-test adjusted by the Holm–ŠÃdák method with α set to 5%). c, Measurement of IFN-γ in lungs of MC-38-stimulated +/+ and tm1a/tm1a male mice (two-tailed unpaired t-test with Welch’s correction). d, e, The proportion of NK cell subsets present in the lungs of naive +/+ versus tm1a/tm1a female mice (d) and control versus Spns2tm1c/tm1c; Lyve1cre/+ male mice (e) (multiple two-tailed unpaired t-tests with P value adjusted by the Holm–ŠÃdák method with α set to 5%). Symbols represent individual mice, horizontal bars represent mean; data shown are representative of three independent experiments.
