Supplementary Figure 14: MutSig quantile–quantile plot for endometrial cancer (UCEC).
From: Analysis of somatic microsatellite indels identifies driver events in human tumors
Quantile-quantile plot of observed vs. expected P-values for MSI-H cases using only previously identified mutations (red) and using previously identified mutations and MS indels (green). Using MutSig for datasets with large numbers of MS indels leads to an inflation in the number of significantly mutated genes.
