Supplementary Figure 2: Sequencing coverage across motifs.
From: Analysis of somatic microsatellite indels identifies driver events in human tumors
The number of MS loci per length for different motifs (A, C, AC, and AG) across the exome is shown in red while the average number of MS loci covered by at least 10 reads is shown in blue. The number of MS loci covered at 10x depth decreases more rapidly than the number of MS loci, demonstrating the difficulty in achieving sufficient coverage for longer repeat lengths. Together, the motifs A, C, AC, and AG represent 98% of MS loci in the exome.
