Figure 3: Association plots for six regions with SNPs showing genome-wide significant association to hair traits.

(a) 2q12 hair shape, (b) 2q12 beard thickness, (c) 16p11 hair shape, (d) 3q22 eyebrow thickness, (e) 2q36 monobrow, (f) 6q25 hair greying. The index SNP in each region (Table 1) is shown as a purple diamond. At the top of the figure are shown the association results (on a -log₁₀ P scale; left y axis) for all genotyped and imputed SNPs. The dot colour indicates the strength of LD (r²) between the index SNP and each SNP (based on the 1000genomes AMR data set). Recombination rate across the region, in the AMR data, is shown as a continuous blue line (scale on the right y axis). Genes in the region are shown in the middle. These plots were produced using LocusZoom⁶⁸. Below each LocusZoom plot we show an LD heatmap (using r², red indicating r²=1 and white indicating r²=0) produced using Haploview⁶⁹. Coordinates used are from human genome sequence build 37. Plots for regions not shown here are presented in Supplementary Fig. 8.