Figure 3: Aggregate copy number profiles. | Nature Communications

Figure 3: Aggregate copy number profiles.

From: Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma

Figure 3

Aggregate copy number profiles of chromosomes 12 (a), 5 (b) and 17 (c) in 112 osteosarcomas are shown in comparison with chromosome 12 of 643 cases of glioblastoma multiforme (d) and to chromosome 17 of 267 soft tissue sarcomas (e). Using copy number calls from this and other studies, aggregate copy number profiles for each chromosome and tumour type were generated. Blue shaded area highlights the first and third quartiles of copy numbers in each genomic position. Black represents the mean copy number in each genomic position. The x axis shows genomic position and the y axis shows copy number change (log2). Putative target genes are indicated with arrows.

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