Figure 4: NMR analysis of peptides.
From: Tyrosine-mediated two-dimensional peptide assembly and its role as a bio-inspired catalytic scaffold
(a–c) Resonance assignments of YYACAYY peptide were analysed after 0 h (a), 24 h (b), 48 h (c) of adding DMSO for oxidative disulphide bond formation. In panels a–c, resonance assignments of monomer and dimer are presented in blue- and black-line. They show that monomeric YYACAYY oxidizes to dimer with appearance of non-sequential NOE connectivities as incubation period increases. (d) Summary of NOE connectivities of dimer YYACAYY peptide. (e) Lowest energy NMR structure of dimeric peptide. The molecular structure are shown with a stick model where carbon, oxygen and nitrogen are presented in grey, red and purple, respectively. Helically coiled peptide backbones are visualized as a green ribbon. (f) Ramachandran plot of 20 lowest energy NMR structures for dimeric YYACAYY.
