Figure 6: Single-molecule reaction dynamics.
From: Single-molecule chemical reaction reveals molecular reaction kinetics and dynamics
(a) Trajectory of turnover rate (s−1) for a single dye molecule at 0.45 mM NaBH4 and 1.3 mM O2. Data points are calculated every five turnovers. (b,c) Autocorrelation functions of τon and τoff derived from the same trajectory as that in a. Solid lines are the exponential fits with decay constants of mon=2.3±0.7 and moff=13.3±5.5 turnovers. Insets: Histograms of fluctuation correlation times for τon (k2) and τoff (k3). (d) Mapping of Brownian motion of a single dye molecule inside a hollow SiO2 nanosphere with optical super-resolution imaging. The dotted circle indicates the inner cavity of the nanosphere; the solid one indicates the centre area of the cavity. Top left: the distribution of the dye in x-direction; Bottom right: the distribution of the dye in y-direction; Top right: a typical transmission electron microscopy image of a hollow SiO2 nanosphere, the scale bar, 200 nm.
