Supplementary Figure 11: Genes at FOXA2-enriched signals are downregulated in Foxa1/Foxa2 null mice. | Nature Genetics

Supplementary Figure 11: Genes at FOXA2-enriched signals are downregulated in Foxa1/Foxa2 null mice.

From: Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

Supplementary Figure 11

Pancreatic islet gene expression data were obtained from wild-type and Foxa1/Foxa2 knockout mice (Gao et al.47). Genes within 500 kb of each FOXA2-enriched T2D signal and closest to each FOXA2-enriched signal (orange) were significantly downregulated in the Foxa1/Foxa2 knockout compared to all genes (gray).

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