Supplementary Figure 9: Forest plot of rs143332484 (TREM2) association with LOAD in combined (stage 1 + stage 2 + stage 3) analysis, shown by each cohort independently analyzed. | Nature Genetics

Supplementary Figure 9: Forest plot of rs143332484 (TREM2) association with LOAD in combined (stage 1 + stage 2 + stage 3) analysis, shown by each cohort independently analyzed.

From: Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Supplementary Figure 9

Cohort-specific odds ratios (ORs) are provided and denoted by blue squares, with 95% confidence intervals (CIs) denoted by blue lines. Individual study OR and combined OR are calculated using the SeqMeta package. The combined OR estimate for each cohort is represented by the blue diamond, where diamond width corresponds to 95% confidence interval bounds. Square and diamond heights are inversely proportional to the precision of the OR estimate.

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