Supplementary Figure 11: Regional plots of the conditional analyses performed at the TREM2 locus in the stage 1 data set. | Nature Genetics

Supplementary Figure 11: Regional plots of the conditional analyses performed at the TREM2 locus in the stage 1 data set.

From: Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Supplementary Figure 11

(a) When conditioning on rs75932628 (p.R47H), indicated in purple, the most significant association is seen with rs143332484 (p.R62H) (P = 3.38 × 10–9). (b) When conditioning on rs143332484 (p.R62H), indicated in purple, the most significant association is seen with (rs75932628 (p.R47H) P = 5.12 × 10–12). (c) When conditioning on both rs143332484 (p.R62H) and rs75932628 (p.R47H), both indicated in purple, the most significant association is seen with rs143539514 (P = 1.51 × 10–3).

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