Supplementary Figure 5: D2 receptor antagonist sulpiride differentially modulated msNAc iSPN intrinsic excitability in slices from Sham and SNI animals.
From: The indirect pathway of the nucleus accumbens shell amplifies neuropathic pain

Representative traces showing depolarizing current injections induced firing in msNAc iSPNs from Sham (a, n = 5 neurons from 5 mice) and SNI animals (c, n = 5 neurons from 5 mice) before and during sulpiride application. Sulpiride (5 µM) increased excitability of iSPNs in Sham (b, W = 1666, p < 0.0001), but had no effect in SNI slices (d, W = 343, p = 0.0524). Data are presented as median with shaded interquartile (quartile 1 to quartile 3), and analyzed using Wilcoxon test.