Figure 5
Effects of receptor depletion with β-FNA on the locomotor response to fentanyl. Effects of fentanyl (F0.3; 0.3 mg/kg s.c.) and saline on locomotor activity in h/mOPRM1-118AA (black bars; n=14) and 118GG (yellow bars; n=13) mice before and after administration of β-funaltrexamine (β-FNA; 3.0 mg/kg s.c.). Values represent mean±SEM. *p<0.05 vs h/mOPRM1-118AA; #p<0.05 vs vehicle; +p<0.05 vs previous drug challenge.
