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Deciphering the genome structure and paleohistory of Theobroma cacao
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  • Published: 16 September 2010

Deciphering the genome structure and paleohistory of Theobroma cacao

  • Cristian Chaparro1,
  • Florent Murat2,
  • John Carlson3,
  • Valentin Guignon4,
  • Mathias Tahi5,
  • Emmanuel Guiderdoni4,
  • Thierry Legavre4,
  • Olivier Fouet4,
  • Erika Sallet6,
  • Xavier Sabau4,
  • Joseph Moroh Akaza5,
  • Francis Quetier7,
  • Mark Guiltinan8,
  • Julie Poulain9,
  • Schiex T.10,
  • Michael Axtell11,
  • Bertrand Pitollat4,
  • Olivier Panaud1,
  • Siela Maximova8,
  • Manuel Ruiz4,
  • Anne Dievart4,
  • Zhaorong Ma11,
  • Karina Gramacho12,
  • Patrick Wincker9,
  • Yolande Roguet4,
  • Melissa Kramer13,
  • Yufan Zhang14,
  • Angélique D’Hont4,
  • Stephanie Sidibe-Bocs4,
  • Claire Lanaud4,
  • Xavier Argout4,
  • Maguy Rodier-Goud4,
  • Laura Gelley13,
  • Spencer Brown15,
  • Dominique Brunel16,
  • Diogenes Infante17,
  • Jerome Salse2,
  • Jose Fernandes Barbosa-Neto1,
  • Zi Sh14,
  • Mickael Bourge15,
  • Wolfgang Golser18,
  • Ismael Kebe5,
  • Jean Marc Aury9,
  • Francois Sabot1,
  • Aurélie Bérard16,
  • Christopher Viot4,
  • Xiang Song18,
  • Pierre Costet19,
  • Gaetan Droc4,
  • Dave Kudrna18,
  • Jetty Siva Ammiraju18,
  • Michel Boccara4,
  • Didier Clement4,
  • Rod Wing18,
  • Jerome Gouzy6,
  • Michael Abrouk2,
  • Stephan Schuster20,
  • Ange Marie Risterucci4,
  • Ronan Rivalan4,
  • W. Richard McCombie13 &
  • …
  • Mathilde Allegre4 

Nature Precedings (2010)Cite this article

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Abstract

We sequenced and assembled the genome of Theobroma cacao, an economically important tropical fruit tree crop that is the source of chocolate. The assembly corresponds to 76% of the estimated genome size and contains almost all previously described genes, with 82% of them anchored on the 10 T. cacao chromosomes. Analysis of this sequence information highlighted specific expansion of some gene families during evolution, for example flavonoid-related genes. It also provides a major source of candidate genes for T. cacao disease resistance and quality improvement. Based on the inferred paleohistory of the T. cacao genome, we propose an evolutionary scenario whereby the ten T. cacao chromosomes were shaped from an ancestor through eleven chromosome fusions. The T. cacao genome can be considered as a simple living relic of higher plant evolution.

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Authors and Affiliations

  1. UMR 5096 CNRS-IRD-UPVD, Laboratoire Génome et Développement des Plantes, Université de Perpignan, 52 Avenue Paul Alduy, 66860 Perpignan Cedex, France

    Cristian Chaparro, Olivier Panaud, Jose Fernandes Barbosa-Neto & Francois Sabot

  2. Institut National de la Recherché Agronomique UMR 1095, 63100 Clermont-Ferrand, France

    Florent Murat, Jerome Salse & Michael Abrouk

  3. Penn State University, The School of Forest Resources and the Huck Institutes of the Life Sciences, University Park, PA 16802, USA and The Department of Bioenergy Science and Technology (WCU), Chonnam National University, 333 Yongbongro, Buk-Gu, Gwangju https://www.nature.com/nature

    John Carlson

  4. CIRAD - Biological Systems Department – UMR DAP TA A 96/03- 34398, Montpellier, cedex 5- France https://www.nature.com/nature

    Valentin Guignon, Emmanuel Guiderdoni, Thierry Legavre, Olivier Fouet, Xavier Sabau, Bertrand Pitollat, Manuel Ruiz, Anne Dievart, Yolande Roguet, Angélique D’Hont, Stephanie Sidibe-Bocs, Claire Lanaud, Xavier Argout, Maguy Rodier-Goud, Christopher Viot, Gaetan Droc, Michel Boccara, Didier Clement, Ange Marie Risterucci, Ronan Rivalan & Mathilde Allegre

  5. Centre national de la recherche agronomique (CNRA), B.P. 808, Divo, Côte d’Ivoire https://www.nature.com/nature

    Mathias Tahi, Joseph Moroh Akaza & Ismael Kebe

  6. INRA-CNRS LIPM Laboratoire des Interactions Plantes Micro-organismes, BP 52627, 31326 Castanet Tolosan Cedex, France

    Erika Sallet & Jerome Gouzy

  7. Département de Biologie, Université d’Evry Val d'Essonne, 25 boulevard François Mitterrand, 91025 Evry, France

    Francis Quetier

  8. Penn State University, Department of Horticulture and the Huck Institutes of the Life Sciences, University Park, PA 16802, USA

    Mark Guiltinan & Siela Maximova

  9. Genoscope (CEA) and UMR 8030 CNRS-Genoscope-Université d’Evry, 2 rue Gaston Crémieux, BP5706, 91057 Evry, France

    Julie Poulain, Patrick Wincker & Jean Marc Aury

  10. Unité de Biométrie et d’Intelligence Artificielle (UBIA), UR875 INRA, F-31320 Castanet Tolosan France https://www.nature.com/nature

    Schiex T.

  11. Penn State University, Bioinformatics and Genomics Ph.D. Program &Department of Biology, University Park, PA 16802, USA

    Michael Axtell & Zhaorong Ma

  12. CEPLAC, Km 22 Rod. Ilheus Itabuna, Cx. postal 07, Itabuna 45600-00, Bahia, Brazil

    Karina Gramacho

  13. Cold Spring Harbor Laboratory, NY, 11723, USA

    Melissa Kramer, Laura Gelley & W. Richard McCombie

  14. Penn State University, Plant Biology Graduate Program and the Huck Institutes of the Life Sciences, University Park, PA, 16802, USA

    Yufan Zhang & Zi Sh

  15. Institut des Sciences du Végétal, UPR 2355, CNRS, 91198 Gif-Sur-Ivette, France

    Spencer Brown & Mickael Bourge

  16. INRA, UR 1279 Etude du Polymorphisme des Génomes Végétaux, CEA Institut de Génomique, Centre National de Génotypage, 2, rue Gaston Crémieux, CP5724, 91057 Evry, France

    Dominique Brunel & Aurélie Bérard

  17. Centro Nacional de Biotecnología Agrícola, Instituto de Estudios Avanzados, Caracas, 1015-A, Venezuela

    Diogenes Infante

  18. Arizona Genomics Institute and School of Plant Sciences, University of Arizona, Tucson AZ 85721, USA

    Wolfgang Golser, Xiang Song, Dave Kudrna, Jetty Siva Ammiraju & Rod Wing

  19. Chocolaterie VALRHONA, 8, quai du général de Gaulle, 26600 Tain l’Hermitage, France

    Pierre Costet

  20. Penn State University, Department of Biochemistry and Molecular Biology, University Park, PA, 16802, USA

    Stephan Schuster

Authors
  1. Cristian Chaparro
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  2. Florent Murat
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  3. John Carlson
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  4. Valentin Guignon
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  5. Mathias Tahi
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  6. Emmanuel Guiderdoni
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  7. Thierry Legavre
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  8. Olivier Fouet
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  9. Erika Sallet
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  10. Xavier Sabau
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  11. Joseph Moroh Akaza
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  12. Francis Quetier
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  14. Julie Poulain
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  15. Schiex T.
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  16. Michael Axtell
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  17. Bertrand Pitollat
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  18. Olivier Panaud
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  19. Siela Maximova
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  20. Manuel Ruiz
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  21. Anne Dievart
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  22. Zhaorong Ma
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  23. Karina Gramacho
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  24. Patrick Wincker
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  25. Yolande Roguet
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  26. Melissa Kramer
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  27. Yufan Zhang
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  28. Angélique D’Hont
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  29. Stephanie Sidibe-Bocs
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  30. Claire Lanaud
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  31. Xavier Argout
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  32. Maguy Rodier-Goud
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  33. Laura Gelley
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  34. Spencer Brown
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  36. Diogenes Infante
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  37. Jerome Salse
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  38. Jose Fernandes Barbosa-Neto
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  39. Zi Sh
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  40. Mickael Bourge
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  41. Wolfgang Golser
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  47. Xiang Song
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  48. Pierre Costet
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  49. Gaetan Droc
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  50. Dave Kudrna
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  51. Jetty Siva Ammiraju
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  52. Michel Boccara
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  53. Didier Clement
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  54. Rod Wing
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  58. Ange Marie Risterucci
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  60. W. Richard McCombie
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  61. Mathilde Allegre
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Cite this article

Chaparro, C., Murat, F., Carlson, J. et al. Deciphering the genome structure and paleohistory of Theobroma cacao. Nat Prec (2010). https://doi.org/10.1038/npre.2010.4908.1

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  • Received: 16 September 2010

  • Accepted: 16 September 2010

  • Published: 16 September 2010

  • DOI: https://doi.org/10.1038/npre.2010.4908.1

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Keywords

  • cocoa
  • cacao
  • genome
  • sequence
  • Theobroma cacao
  • Evolution
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