Fig. 1 | Journal of Human Genetics

Fig. 1

From: Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease

Fig. 1

a Manhattan plot of −log10 P values of the SNP-based association analysis of morning plasma cortisol (n = 25,314). The locus on chr14 spans SERPINA6 and SERPINA1 genes; no other loci reached genome-wide significance. b, c Zoomed in Manhattan plot (LocusZoom plot) of −log10 P values of the SNP-based association analysis of morning plasma cortisol (n = 25,314). These show two (of the four) LD blocks (r2 > 0.3) in this locus

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