Fig. 6 | Experimental & Molecular Medicine

Fig. 6

From: USP15 inhibits multiple myeloma cell apoptosis through activating a feedback loop with the transcription factor NF-κBp65

Fig. 6

PDTC treatment inhibits USP15 overexpression-induced cell proliferation and apoptosis inhibition in MM. After RPMI 8226 and U266 cells cultured in complete medium containing either PDTC (50 μM) or no inhibitors were transfected with pLVX-Puro-USP15, proliferation was measured with the CCK-8 assay (a, b) and apoptosis was measured by flow cytometry with Annexin V-FITC/PI staining (c, d). ***P < 0.001 compared with vector. ###P < 0.001 compared with USP15

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