Fig. 8
From: LITTIP/Lgr6/HnRNPK complex regulates cementogenesis via Wnt signaling
LITTIP/Lgr6/HnRNPK complex plays a crucial role in regulating cementogenesis. a Relative mRNA expression of cementogenesis-related genes. The mRNA expression of Runx2, Osx and CAP in OCCM-30 cells was decreased by overexpression of LITTIP, and increased when the complex function was inhibited by si-HnRNPK. n = 6; *P < 0.05, ***P < 0.001. b Western blotting showed the protein levels of Runx2, Osx and CAP in OCCM-30 cells. c–e Representative images and quantitative analysis of ALP and ARS staining. n = 6; ***P < 0.001. f Schematic diagram showed that LITTIP promoted LGR6 expression via the LITTIP-binding protein HnRNPK
