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Correlation between different types of obesity and hypertension in perimenopausal working women

Journal of Human Hypertension volume 39, pages 343–347 (2025)Cite this article

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Abstract

Hypertension (HTN) can lead to a series of target organ damage and is associated with increased cardiovascular disease incidence and mortality. Perimenopause implies an important physiological transition. Previous studies have confirmed that obesity is a risk factor for the development of HTN. Nevertheless, few studies have investigated the prevalence of HTN in perimenopausal women and the relationships between peripheral or abdominal obesity and HTN. Therefore, we analysed the influencing factors of HTN in perimenopausal working women and the correlation between different types of obesity and HTN to provide evidence for the need to prevent HTN in perimenopausal women. Perimenopausal women who underwent physical examination at Shanghai Health and Medical Center from January 2021 to October 2021 were selected as subjects. A multivariate logistic regression model was used to analyse the associations between different types of obesity and HTN in perimenopausal women. Five hundred eighty-two perimenopausal women were included in this study; 124 cases of HTN were detected (incidence rate 21.31%), 23 of which were isolated systolic HTN (18.55% of total HTN cases). Multivariate logistic regression analysis revealed that age and BMI were the influencing factors of HTN in perimenopausal women. Compared with that of perimenopausal women without peripheral obesity, HTN in overweight (OR = 1.84, 95% CI: 1.13–2.98) and peripheral obesity (OR = 4.36, 95% CI: 1.52–12.54) women increased with increasing body weight. Perimenopausal women with abdominal obesity had a greater risk of developing HTN (OR = 2.69, 95% CI: 1.16–6.21) (P < 0.05). Age and BMI are risk factors for the development of HTN in perimenopausal working women. Both abdominal obesity and peripheral obesity are positively associated with HTN in perimenopausal women. The BMI and abdominal circumference of perimenopausal women need to be monitored as early as possible to prevent obesity and reduce the occurrence of HTN.

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Acknowledgements

The authors thank all the investigators who participated in the study and all the participants.

Funding

This study has been supported by Research on health management strategy and application of elderly population (GWVI-11.1-28). The funding body did not influence the design of the study, the collection, analysis, and interpretation of data, and on writing the manuscript.

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Author notes

  1. These authors contributed equally: Huaiqin Zhong, Yan Qiu, Zhuoqun Zou.

Authors and Affiliations

  1. Gerontology Department, Shanghai Health and Medical Center, Wuxi, Jiangsu Province, China

    Huaiqin Zhong, Yan Qiu, Xvping Zhu, Jinyu Li & Zhuoqun Zou

  2. Medical Department, Shanghai Health and Medical Center, Wuxi, Jiangsu Province, China

    Mei Liu

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  1. Huaiqin Zhong
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  2. Yan Qiu
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Contributions

Zhuoqun Zou contributed to the study concept and design, interpreting the data, composing the statistical dataset, performing the analyses, and writing and revising the manuscript. Huaiqin Zhong contributed to data acquisition, data curation, concept, and drafting of the manuscript. Yan Qiu contributed to data acquisition, data curation, concept, and drafting of the manuscript. Xvping Zhu contributed to interpreting the data and critically revising the manuscript. Mei Liu and Jinyu Li contributed to interpreting the data and critical revision of the manuscript. All the authors reviewed and approved the final version, and no other person made a substantial contribution to the paper.

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Correspondence to Zhuoqun Zou.

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Competing interests

The authors declare no competing interests.

Ethical approval

This study was performed in line with the principles of the Declaration of Helsinki and approved by the Ethics Committee of Shanghai Health and Medical Center(2020-No.07). Informed consent was obtained from all individual participants included in the study.

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Zhong, H., Qiu, Y., Zhu, X. et al. Correlation between different types of obesity and hypertension in perimenopausal working women. J Hum Hypertens 39, 343–347 (2025). https://doi.org/10.1038/s41371-025-01010-y

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