Fig. 1 | Laboratory Investigation

Fig. 1

From: Surfactant dysfunction and alveolar collapse are linked with fibrotic septal wall remodeling in the TGF-β1-induced mouse model of pulmonary fibrosis

Fig. 1

Lung mechanics. Tissue elastance (a) and quasi-static compliance (b) were used to characterize the lung mechanical properties in the study groups on day 7 (D7) and day 14 (D14). Surf groups were treated with intratracheal surfactant (poractant alpha) on days 3 and 6 after adenoviral-mediated gene transfer of active TGF-β1 (AdTGF-β1), whereas saline groups received 0.9% sodium chloride solution. The control group demonstrates healthy conditions for comparison. n.s.: not significant

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