Fig. 8 | Laboratory Investigation

Fig. 8

From: Surfactant dysfunction and alveolar collapse are linked with fibrotic septal wall remodeling in the TGF-β1-induced mouse model of pulmonary fibrosis

Fig. 8

Correlation analyses between alveolar microarchitecture, lung mechanics, and remodeling. Abnormal alveolar microarchitecture is linked with lung mechanical impairment regarding tissue elastance (a) and quasistatic compliance (b). At D14, abnormal alveolar microarchitecture [alveolar number (c, d); volume-weighted mean alveolar volume (e, f)] was correlated to the deposition of collagen fibrils in septal wall tissue (c, e) and the decline of the apical membrane surface area of AE2 cells per lung (d, f)

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