Fig. 5: AOPPs-induced nuclear translocation of NF-κB. | Laboratory Investigation

Fig. 5: AOPPs-induced nuclear translocation of NF-κB.

From: Advanced oxidation protein products downregulate CYP1A2 and CYP3A4 expression and activity via the NF-κB-mediated signaling pathway in vitro and in vivo

Fig. 5

AOPPs increased nuclear translocation of NF-κB detected in the nuclear protein by laser confocal microscopy (400×) in HepG2 (A) and L-02 cells (B). Cytoplasmic and nuclear protein expression levels of NF-κB were detected by western blotting (C). Protein expression levels were quantified by ImageJ software (D). Each experiment was performed with a different isolate. Data are presented as mean ± SD; *p < 0.05 compared with the CON group. Data were normalized to GAPDH.

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