Fig. 4: mRNA expression profile changes in the control, pH 6.0, and pH 6.0+nesfatin-1 groups. | Laboratory Investigation

Fig. 4: mRNA expression profile changes in the control, pH 6.0, and pH 6.0+nesfatin-1 groups.

From: Nesfatin-1 exerts protective effects on acidosis-stimulated chondrocytes and rats with adjuvant-induced arthritis by inhibiting ASIC1a expression

Fig. 4

A Heat map showing differentially expressed mRNAs with the same expression pattern in control and pH 6.0+nesfatin-1 groups, which was the opposite of that noted in the pH 6.0 group. B Venn diagram showing the number of overlapping mRNAs in the three groups. C KEGG enrichment analysis of co-differentially expressed genes in the control and pH 6.0 groups. D KEGG enrichment analysis of co-differentially expressed genes in the pH 6.0 and pH 6.0+nesfatin-1 groups.

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