Fig. 2: GTSE1 is upregulated in ccRCC and predicts poor clinical outcomes. | Laboratory Investigation

Fig. 2: GTSE1 is upregulated in ccRCC and predicts poor clinical outcomes.

From: GTSE1 promotes tumor growth and metastasis by attenuating of KLF4 expression in clear cell renal cell carcinoma

Fig. 2

qRT-PCR (A) and Western blot (B) analysis of GTSE1 expression levels in ccRCC tissues and paired adjacent normal tissues. Real-time quantitative polymerase chain reaction (qRT-PCR) (C) and Western blot (D) analysis of GTSE1 expression levels in ccRCC cell lines and normal human kidney epithelial cell lines. Representative Tissue micro-array (TMA) images show GTSE1 staining (E), and comparison of the Immuno-histochemistry (IHC) score between tumor and non-tumor renal tissues (F). The expression of GTSE1 in different clinical stages and metastasis status: clinical stage (G), lymphatic metastasis (H) and distant metastasis (I). J, K OS and DFS curve of TMA patients based on GTSE1 expression according to Kaplan-Meier analysis. OS curve (J), DFS curve (K). L, M OS curve of TMA patients with different GTSE1 expression was further analyzed according to clinical stage. stage I,II (L) or stage III,IV (M). The n values indicate the number of patients. Error bars represent SD of the mean. **p < 0.01, ***p < 0.001, ****p < 0.0001.

Back to article page