Fig. 9: NOB promotes Nrf2 nuclear translocation and upregulates HO-1 expression in RGCs. | Laboratory Investigation

Fig. 9: NOB promotes Nrf2 nuclear translocation and upregulates HO-1 expression in RGCs.

From: Nobiletin protects retinal ganglion cells in models of ocular hypertension in vivo and hypoxia in vitro

Fig. 9

A Representative immunofluorescence images of Nrf2 at 2 weeks post-IOP elevation. Scale bar, 50 μm. B Representative Western blot for nuclear and cytoplasmic Nrf2. C Quantification of nuclear Nrf2 Western blot normalized to H3. D Quantification of cytoplasmic Nrf2 Western blot normalized to β-actin. The results are expressed as mean ± SD, n = 6. *P < 0.05, **P < 0.01.

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