Fig. 2: Silencing of lncRNA DLGAP1-AS1 restricts NCl-H1975 cell viability, migration, and invasion but induces apoptosis in NCl-H1975 cells. | Laboratory Investigation

Fig. 2: Silencing of lncRNA DLGAP1-AS1 restricts NCl-H1975 cell viability, migration, and invasion but induces apoptosis in NCl-H1975 cells.

From: Long non-coding RNA DLGAP1-AS1 modulates the development of non-small-cell lung cancer via the microRNA-193a-5p/DTL axis

Fig. 2

A The expression of lncRNA DLGAP1-AS1 in NCl-H1975 cells determined by RT-qPCR. B The viability of NCl-H1975 cells assessed by CCK-8 assay. C The apoptosis of NCl-H1975 cells measured by flow cytometry. D The NCl-H1975 cell migration measured by Transwell assay (× 200, scale bar = 50 µm) E The NCl-H1975 cell invasion measured by Transwell assay (× 200, scale bar = 50 µm); *p < 0.05, vs. NCl-H1975 cells transfected with sh-NC; Values were expressed as the mean ± standard deviation; data between two groups were compared with unpaired t-test and data among multiple groups were compared with one-way ANOVA, followed by a Tukey multiple comparisons posttest; Values of cell viability were analyzed using ANOVA of repeated measurements, followed by a Bonferroni post hoc test for multiple comparisons; the experiment was repeated 3 independent times.

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