Fig. 6: Silencing of lncRNA DLGAP1-AS1 inhibits NSCLC tumor growth in vivo via the miR-193a-5p/DTL axis. | Laboratory Investigation

Fig. 6: Silencing of lncRNA DLGAP1-AS1 inhibits NSCLC tumor growth in vivo via the miR-193a-5p/DTL axis.

From: Long non-coding RNA DLGAP1-AS1 modulates the development of non-small-cell lung cancer via the microRNA-193a-5p/DTL axis

Fig. 6

A Representative images of tumors resected from nude mice. B Tumor volume. C Tumor weight. D Relative expression of lncRNA DLGAP1-AS1, miR-193a-5p and DTL determined by RT-qPCR. E Relative protein expression of DTL determined by Western blot analysis; *p < 0.05, vs. nude mice harboring NCl-H1975 cells transfected with sh-NC; #p < 0.05, vs. nude mice harboring NCl-H1975 cells transfected with sh-DLGAP1-AS1; n = 10; Values were expressed as the mean ± standard deviation; data among multiple groups were compared with one-way ANOVA, followed by a Tukey multiple comparisons posttest; Values of cell viability were analyzed using ANOVA of repeated measurements, followed by a Bonferroni post hoc test for multiple comparisons; the experiment was repeated 3 independent times.

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