Table 1 Patient characteristics of the Discovery (mIHC) and Validation (FC) cohort subjects included in survival analyses

From: Immune cell constitution in bone marrow microenvironment predicts outcome in adult ALL

Variable

mIHC (n = 44)

FC (n = 31)

 Gender, female (%)

45

35

 Gender, male (%)

55

65

 AlloHSCT (%)

55

52

Diagnostic data (median, range)

  Age (years)

47 (16–72)

43 (19–69)

  Ph+ (%)

57

42

  CD20+ (%)

36

58

  Leukocytes (10E9/l)

15.6 (0.4–174)

18.4 (0.9–188.5)

  Platelets (10E9/l)

47 (3–233)

45 (3–252)

  BM blasts (%)

90 (50–100)

90 (50–100)

  WHOa ≥1 (%)

66

71

  1. There were no significant differences between the cohorts (Mann–Whitney U test for continuous and Fisher’s exact test for categorical variables). The lowest pretreatment platelet count ±2 days around the diagnosis date was selected
  2. alloHSCT allogeneic hematopoietic stem cell transplantation, BM bone marrow, mIHC multiplexed immunohistochemistry, FC flow cytometry
  3. aWHO/ECOG performance scale
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