Fig. 1

Genetic alterations involving PD-1 ligands in various subtypes of lymphomas. a Frequency of genetic alterations involving PD-L1 and/or PD-L2 in each lymphoma subtype. Type of alterations is indicated by color. Cases harboring both SV and focal CNA affecting PD-L1 and/or PD-L2 are combined into the corresponding SV group. Multiple represents cases harboring both PD-L1 and PD-L2 SVs. DLBCL, diffuse large B-cell lymphoma; FL, follicular lymphoma; MALT, mucosa-associated lymphoid tissue lymphoma; MCL, mantle cell lymphoma; PMBCL, primary mediastinal B-cell lymphoma; PTCL-NOS, peripheral T-cell lymphoma-not otherwise specified; ENKTL, extranodal NK/T-cell lymphoma; ANKL, aggressive NK-cell leukemia; EBV T-LPD, Systemic EBV-positive T-cell lymphoproliferative disorder; Amp, amplification. b, c Different types of SVs affecting PD-L1 (b) and PD-L2 (c) are shown by indicated colors