Fig. 5 | Leukemia

Fig. 5

From: Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas

Fig. 5

Genetic differences between EBV-negative and -positive DLBCLs. a Frequency and type of somatic alterations identified by targeted-capture sequencing for lymphoma-associated genes in 48 EBV-negative and 27 EBV-positive DLBCL cases. Type of alterations is indicated by color. BCR, B-cell receptor; GCB, germinal center B-cell. *P < 0.05, **P < 0.01, Fisher’s exact test. b Distribution of somatic mutations encoded in MYD88 (NM_002468), CD79B (NM_000626), TET2 (NM_001127208), and FAS (NM_000043) detected in 48 EBV-negative and 27 EBV-positive DLBCL cases. The protein domains were obtained from the NCBI Gene database (https://www.ncbi.nlm.nih.gov/gene/) and the UniProt database (https://www.uniprot.org/)

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