Fig. 1
Best percentage change from baseline in peripheral blood lymphocyte count by patient. a Patients presented with del(17p) and/or TP53 mutation. b Patients had a baseline lymphocyte count of <4 × 109/L. c Patients had a best percentage change from baseline to a lymphocyte count of <4 × 109/L. d Patient was randomized to 200 mg but was escalated to 400 mg. e Patient was randomized to 9 mg but was escalated to 25 mg. f Patient was randomized to 800 mg but was de-escalated to 600 mg in cycle 3 and received 800 mg again by error in cycle 4. g Patients received only the predose, i.e., the first part of the split infusion of BI 836826 in cycle 1, which was 10% of the total dose, but maximally 10 mg
