Fig. 5: In vivo tumor eradication.
From: Fiber-optic drug delivery strategy for synergistic cancer photothermal-chemotherapy
a Schematic illustration and timeline of the photothermo-chemotherapy using the optic-fiber therapeutic probe with Dox@Agarose. b Temperature monitoring by FBG. Insert: The real treatment image on the left and the thermal image of mice bearing tumors during treatment on right. c The monitoring of MZI wavelength shift during the treatment. d Statistical distinctions among the groups at several typical time ends. Statistical analysis is performed by Student’s t test (t test). *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.001. e Corresponding growth curves of tumors in different groups of mice at a measured time; V0 means the volume before treatment. The volume (mm3) = 1/2 × (tumor length) × (tumor width)2 (n = 6). f Kaplan-Meier survival curve of mice after different treatments. g Body weight of nude mice recorded every 3 days after treatment. h The tumor growth curves of each mouse in different groups. i Representative photographs of mice bearing in different groups sets before and after various treatments
